This fifth annual Summit will provide opportunities to hear from leaders in quantum information science and engineering who are at the forefront of – and defining – this emerging field. These experts will share their insights and experiences growing government research initiatives, industry technology development, and building a quantum workforce. The two-day program will include industry and government presentations on the future of quantum information science and technology, dialogue on growing the quantum economy, and will include the 2022 Quantum Creators Prize Symposium which will promote early-career researchers working in new directions of quantum science.