The extraordinary advances in quantum control of matter and light have been transformative for precision measurements enabling probes of the most basic laws of Nature to gain fundamental understanding of the physical Universe. Exceptional versatility, inventiveness, and rapid development of precision experiments supported by continuous technological advances and improved theory give a high chance for paradigm-shifting discovery. The development of atomic clocks with systematic uncertainties in the 10-18 range enables searches for the variation of fundamental constants, dark matter, and violations of Lorentz invariance. I will give an overview of dark matter searches with clocks including prospects for significantly improved sensitivity with highly charged ions and a nuclear clock. At the end, I will also introduce our new online portal for high-precision atomic data and computations.